From what i understand when a player kills a monster in D3 the monster has a chance of dropping a health/mana globe. Now i know that the mechanic of health/mana orb/potion are currently under work and much has changed that has not been revealed yet. But some players are happy of this as it takes away the potion spamming of D2. But i foresee problems, what if you to a situation where your fighting and no health globes/orbs drop. So to speak, in D2 when the player had to fight the Ancients on the pursuit of Baal. The fight was hard and required potions, if something like this was in D3 how would the player survive ? There is no petty monsters to kill for orbs and your gonna need health before you kill one of the Ancients who might not even drop an orb.

Maybe I'm missing something but I'm worried about this new mechanic, but i know ill be happy with whatever the end results are.

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Q u o t e:
Boss Monsters also have a chance to drop health globes when critically hit, so a player isn't left high and dry in long fights against single foes.

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Rares and Champions have a chance to drop globes when hit.

Uniques/Bosses... ? Maybe! But their health replenishing mechanics (among other things) have a better chance of being a bit more creative since their lairs are specifically designed for them.

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Q u o t e:
Ah, so that's the terminology we're using here.

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As far as I know it right now the terms we're using and what they mean:

Champions - small packs of tougher mobs that have a unique champion trait, one affix, increased health, damage, harder, etc.
Rares - single enemy of great difficulty, can have a few affixes, they're named (randomly), much tougher, comes with a group of minions that inherit their affixes and bonuses
Uniques - Unique boss monsters. Unique name/art/skills/lairs(or specific location) and are usually a part of the story/goal of a quest, if not the actual end-boss of an act. The Skeleton King and the Siegebreaker would both be uniques

[edited for more info/clarity]

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Q u o t e:
Didn't you say a long time ago that the Siege Breaker was Not a unique monster?

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Thousand Pounder?

Maybe. I guess it just depends on what the ultimate use is for the models and such. Siege breaker will probably be unique. It's too big to have a ton of them spawning all over the place.

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Q u o t e:
I assume the chance is going to be quite low?

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It's actually higher.

Regular monsters have a chance to drop a small health globe on death, champions have a chance to drop a bigger health globe once during their life and again at death, and rares have a very high chance to drop an even bigger health globe every quarter of their life and then at death.

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Q u o t e:
So does this confirm that we could possibly see a rare lightning enhanced multi-shot like in D2?

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It's not really new information. The BC'09 demo had champions and rares and a bunch of affixes. But yes, a rare can roll an Electrified and Multi-shot affix already, as well as a third... maybe Teleport! The most annoying of all affixes! At least as a lower level barbarian...

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Q u o t e:
what if im unlucky and my chance to drop a globe doesnt happen, am i screwed? luck based whether i live or die is no fun. I hope it isnt like this. I think im pretty unlucky, if its like 20% to drop globe for example i'll make 50 hits no globe happen if its possible believe me... :(

I like that at certain points of a bosses health 25% 50% etc there is a guarantee globe drop, now thats more controlled.

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There are still health potions should you hit an unlucky streak, or more likely, you get yourself into a bad situation.

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Q u o t e:
So what prevents a player from jumping into a horde of 100 monsters and spamming skills, being kept alive by tons of mana and health potions? Is there a cooldown?

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Yes, potions have cooldowns.

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Q u o t e:
Can you get Health Globes from other source than monsters?

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Most likely.

How would you use a potion that's on cooldown?